Spyridon was born in Assia, in Cyprus. He worked as a shepherd and was known for his great piety.
He performed a great number of miracles which was the main reason why they considered him a saint even before his death.
Saint Spyridon also participated in the First Ecumenical Council of Nicaea (325). Countering the theological arguments of Arius and his followers.
He also served as a Bishop of Trimythous, a district of Larnaca Cyprus, until he died on December 12, 348 A.D. He is commemorated by the church on December 12.